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DeCS
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Descriptor Inglés:
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Nogo Proteins
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Descriptor Español:
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proteínas Nogo
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Descriptor Portugués:
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Proteínas Nogo
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Sinónimos Inglés:
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NI 220 Protein
NI 250 Protein
NI 35 250
NI 35 Protein
NI-220 Protein
NI-250 Protein
NI-35 Protein
NI-35-250
Neurite Growth Inhibitor 35 350
Neurite Growth Inhibitor 35-350
Nogo 66 Protein
Nogo A Protein
Nogo B Protein
Nogo C Protein
Nogo Protein
Nogo-66 Protein
Nogo-A Protein
Nogo-B Protein
Nogo-C Protein
Reticulon 4 B Protein
Reticulon 4 Protein
Reticulon 4-B Protein
Reticulon-4 Protein
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Categoría:
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D12.776.543.620.738
D12.776.631.580.738
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Definición Inglés:
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Myelin proteins that are expressed as three isoforms: Nogo-A, Nogo-B, and Nogo-C. These share a C-terminal reticulon homology domain (RHD), consisting of two hydrophobic membrane domains flanking a 66 amino acid (Nogo-66) hydrophilic region. A long transmembrane region allows conformations that either span the entire membrane or fold into a hairpin conformation. Nogo inhibits NEURITE outgrowth and modulates wiring and the restriction of SYNAPTIC PLASTICITY in the adult central nervous system. It also regulates neurite fasciculation, branching, and extension in the developing nervous system. |
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Nota Histórica Inglés:
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2017 (2000)
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Calificadores Permitidos Inglés:
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Número del Registro:
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56639
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Identificador Único:
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D000070798
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Ocurrencia en la BVS:
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Similar:
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DeCS
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